These three new products from Lamelle do what was previously impossible – they employ cytokines to control the chronic inflammation that’s ageing us

A couple of weeks ago, we told you that scientists discovered what actually causes skin ageing: A silent, chronic type of inflammation that slowly degrades the body over time.

Good news: Lamelle Research Laboratories has introduced three new products to the Dermaheal range that use special enzymes called cytokines to effectively “switch off” chronic inflammation.

How chronic inflammation ages you

Chronic inflammation is when irritants like sunlight, smoke, pollution, cosmetics, perfumes and chemicals, and other factors like stress, bacteria and infections, poor diet etc. trigger free radicals in the skin. The free radicals cause microscopic injuries, which the body tries to heal with its natural inflammation responses.

With any inflammatory immune response, the body releases tissue-break-down enzymes called Matrix Metalloproteinase (MMPs). In the case of normal, local inflammation for healing a wound (when you get a cut or scrape) the MMPs are vital for destroying injured tissue, so the skin can heal and renew.

In the case of chronic inflammation, though, there is no big wound, and thus no injured tissue to destroy. Sadly, the MMPs now start breaking down healthy skin cells. And this is where the trouble lies.

In skin, there are three very dangerous types of MMPs:

  • Collagenase – breaks down collagen
  • Elastinase – breaks down elastin
  • Hyaluronidase – breaks down hyaluronic acid

As you probably already know, the collagen, elastin and hyaluronic acid are vital for healthy skin. In fact, the MMPs caused by chronic inflammation destroy all the elements of healthy skin. And in so doing, chronic inflammation (or inflammaging as it’s often called) accelerates the ageing process.

Fortunately, Lamelle Research Laboratories did all the research and testing, and now know how to “switch off” chronic inflammation by manipulating special enzymes called cytokines.

What are cytokines?

Cytokines are small proteins that cells secrete to help the body stay healthy. They are vital for the immune system to function because (among other functions) cytokines control inflammation in the body.

Cytokines are actually able to instruct a cell to switch the inflammation response on or off. To do this, there are physically different types of cytokines:

  • Pro-inflammatory cytokines – switch inflammation on
  • Anti-inflammatory cytokines – switch inflammation off

Medical Director at Lamelle Research Laboratories, Dr Bradley Wagemaker, and his team recently announced that they’ve isolated the two most powerful “good” anti-inflammatory cytokines, called IL-4 and IL-10. And, by including these in the NEW Dermaheal range, these products now have the remarkable ability to instruct your skin cells to “switch off” chronic inflammation, effectively flipping the switch on accelerated ageing itself.

3 New products containing anti-inflammatory cytokines:

NEW Dermaheal Cellular Repair Cream


  • Anti-inflammatory cytokines (to switch off chronic inflammation)
  • Nobel Prize-winning Recombinant Human Growth Factors technology
  • Pycnogenol® (most powerful antioxidant)
  • Fast-absorbed Vitamin C for resilient collagen and elastin

NEW Dermaheal Renewal Cream


  • Advanced concentrations of anti-inflammatory cytokines
  • Lamelle’s patented Recombinant Human Growth Factors technology
  • The unique antioxidant Astaxanthin
  • Ceramide-P lipid barrier defence

NEW Dermaheal Ultra Renewal Cream


  • Lamelle’s most advanced anti-inflammatory cytokine complex
  • The most advanced blend of Recombinant Human Growth Factors
  • Cell-turnover balancing retinoid
  • Hyaluronic acid fragment (HAFi) technology
  • Ceramide-P lipid barrier defence

All three of these advanced chronic inflammation-supressing products are already available at aesthetic clinics. Ask your therapist for them by name.

Got any inflammaging or ageing questions, tips or ideas? Let us know in the comments below.

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  1. meryl Griffiths October 6, 2016 at 2:15 pm Reply

    Where do I find the prices for the Derma heal

    • lapelle October 13, 2016 at 10:15 am Reply

      Hi Meryl, please feel free to contact Lamelle directly on (011) 465 2264. They will gladly give you your nearest outlets and prices.

  2. Maryna October 8, 2016 at 10:23 am Reply

    Good Day
    I am using the Dermaheal range as recommended by my beauty therapist and is very happy with the products .My skin have a visible smoothness and beauty.
    My age is 58 as I was very scared at first to make a change of products at this age , but it was
    definitely worth,I trust my beauty therapist as she is giving everything every time,always give you individual time as if you are her only client for the day.

    The new range must you use all three at once or only one as recommended by your therapist.
    Can you use it as a day and night cream
    Does the ultra renewal cream contain any sunblock if you use it as a day cream
    Do you recommend to still use a serum with the new products

    Thank you

    • lapelle October 13, 2016 at 10:24 am Reply

      Hi Maryna, your therapist is the right person to ask these question to. That said though, the answers to your question are:
      No, you don’t use all three, you use the one that’s specifically designed for your skin type (your therapist with have to advise whether Daily Cellular, Renewal or Ultra is best for you). These are essentially moisturisers, and would thus be for morning and evening use, but you must consult your therapist and also the instructions on the packaging.
      The Ultra Renewal cream does not offer the advanced sun protection that Helase would offer, ideally you’d use Helase daily to protect and repair + Dermaheal to nourish, rejuvenate and counteract ageing.
      Serums are best used for achieving advanced results over a short period of time. While the Dermaheal range is daily, serums are usually only used seasonally and for a specific outcome, as advised by your therapist. Hope these points helped. If you need any more info, remember you can chat to Lamelle directly by phoning (011) 465 2264.

  3. Carol Pagan October 20, 2016 at 1:13 pm Reply

    What is the cost of each of these face creams and where can i obtain them ?

    • lapelle October 20, 2016 at 1:48 pm Reply

      Hi Carol, thanks for asking. Lamelle Research Laboratories is the supplier, and they have various wonderful aesthetic clinic outlets all over the country. Please phone Lamelle directly on (011) 465 2264. They will be able to direct you to your nearest outlets, and be able to supply prices. Hope this helps!

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